15 Best Patient Portal Software Solutions for 2025: Top Picks

In the digital age of healthcare, patient portal software has become a crucial tool for enhancing patient engagement and improving provider efficiency.

These platforms allow patients to access their medical information, schedule appointments, and communicate with healthcare providers conveniently.

Choosing the best patient portal software can significantly impact the quality and accessibility of healthcare services. 

In this article, readers can expect a comprehensive analysis of top-rated solutions available in 2025, examining their features, benefits, and what sets them apart.

“Be sure to check out Keragon’s automation solutions platform to see how you can improve patient engagement and streamline healthcare operations.”

Best patient portal software vendors: comparison & ratings chart

15 top patient portal systems reviewed

This section provides insights into some of the leading patient portal systems available today. Each system is examined for its key functionalities, user feedback, pricing, and other relevant factors, offering a clear picture of what each software brings to the table.

1. SimplePractice

SimplePractice is widely recognized for its intuitive design, which empowers healthcare professionals to manage their practice efficiently.

Top Features:

• Telehealth: Offers integrated video conferencing, enhancing remote consultations.
• Billing management: Simplifies invoicing and payment tracking.
• Scheduler: Robust calendar features help in managing appointments seamlessly.

Pros:

• User-friendly interface.
• Comprehensive billing tools.
• Reliable telehealth solution.

Cons:

• Limited advanced reporting features.
• Customization can be challenging for new users.

Integrations: SimplePractice seamlessly integrates with several third-party applications, including accounting and telehealth tools.

Support: SimplePractice offers customer service through phone support available Monday to Friday, 7:00 AM to 5:00 PM PT. Live chat is accessible Monday to Friday, 6:00 AM to 6:00 PM PT, and Saturday to Sunday, 7:00 AM to 4:00 PM PT. Email support is available Monday to Friday, 6:00 AM to 7:00 PM PT, and Saturday to Sunday, 6:00 AM to 6:00 PM PT.

Ratings and reviews: SimplePractice enjoys positive feedback for its ease of use and functionality. It consistently receives favorable reviews, with Capterra giving it a rating of 4.7 and G2 rating at 4.6.

Pricing:

• $59/month for the Essential plan.
• $99/month for the Professional plan.

2. EHR YOUR WAY

EHR YOUR WAY is designed for mental health professionals and small clinics, focusing on flexibility and customization.

Top Features:

• Customizable templates: Allows users to tailor their documentation to specific needs.
• Mobile access: Facilitates operations on-the-go.
• Comprehensive reporting: Detailed analytical tools for reviewing patient data.

Pros:

• High customization level.
• Mobile-friendly interface.
• Extensive reporting capabilities.

Cons:

• Steeper learning curve initially.
• Limited integration options.

Integrations: The software offers a selection of basic integrations, mainly with existing healthcare tools.

Support: EHR YOUR WAY provides customer service via phone at (619) 330-6087, available Monday through Friday, 7:00 AM to 5:00 PM PST. For emergencies, 24/7 support is accessible through email at support@ehryourway.com. 

Ratings and reviews: Users appreciate the customizability of EHR YOUR WAY, though it can be complex to learn. It holds a 4.5-star rating on Capterra and 4.4 on G2.

Pricing:

• Basic Plan: $50/month per user.
• Advanced Plan: Custom pricing based on features.

3. Jane

Jane is known for combining simplicity with comprehensive features suitable for various healthcare practices.

Top Features:

• Online booking: Simplifies appointment scheduling.
• Charting: Provides templates for efficient data documentation.
• Payment processing: Built-in tools for handling transactions.

Pros:

• Straightforward booking system.
• Excellent customer service.
• Versatile charting tools.

Cons:

• Some limitations in data export functionalities.
• Not ideal for large practices requiring complex integrations.

Integrations: Jane connects with numerous payment gateways and accounting platforms, enhancing operational efficiency.

Support: Jane offers customer service through phone support available Monday to Friday, 6:00 AM to 5:00 PM PT, and Saturday, 8:00 AM to 12:00 PM PT. Email support is also available, with responses typically within 24 hours.

Ratings and reviews: Jane receives accolades for its practical approach and ease of use, reflected in a Capterra rating of 4.8 and G2 rating of 4.7.

Pricing:

• Solo Plan: $74/month.
• Clinic Plan: $99/month.

4. MidexPRO

MidexPRO delivers an advanced suite of features suitable for various practice sizes, focusing on versatility and regulation compliance.

Top Features:

• Electronic medical records (EMR): Comprehensive EMR tools tailored for diverse needs.
• Patient communication: Streamlined messaging systems.
• Data security: Features focus on HIPAA compliance.

Pros:

• High level of compliance with medical standards.
• Flexible communication channels.
• Robust EMR system.

Cons:

• Can be time-consuming to implement.
• Some users report a complex user interface.

Integrations: Offers integration with laboratory systems and billing software, ensuring a wide operational scope.

Support: MidexPRO offers customer service through phone, email, and live chat, available Monday to Friday, 9:00 AM to 5:30 PM UK time. For assistance outside these hours, sending an email to support@midexpro.com will trigger an automated response with instructions for common issues.

Ratings and reviews: MidexPRO is praised for its comprehensive feature set and compliance focus, rated 4.6 stars on Capterra and 4.5 on G2.

Pricing: Custom pricing is available based on practice requirements and size.

5. Benchmark Solutions Practice Management

Benchmark Solutions focuses on practice management aspects, offering functionality in patient engagement and administrative efficiency.

Top Features:

• Appointment scheduling: Advanced tools for booking management.
• Data analysis: Provides insights for better decision-making.
• Patient engagement: Enhances interaction through portals and reminders.

Pros:

• Strong emphasis on administrative capabilities.
• Valuable insights from analytics.
• Effective patient engagement tools.

Cons:

• May lack advanced clinical features.
• Administrative focus may not suit all practice types.

Integrations: Supports integrations with EMR and financial systems for smoother operations.

Support: Benchmark Solutions provides customer service via phone and email, available Monday through Friday, 8:00 AM to 5:00 PM local time. For urgent matters outside these hours, 24/7 support is accessible through their urgent line and monitored email address.

Ratings and reviews: Users appreciate its administrative focus and ease of use, with a 4.6-star rating on Capterra and 4.5 on G2.

Pricing: Tailored pricing plans based on specific features and practice size.

6. My Clients Plus

My Clients Plus caters primarily to therapists and mental health professionals, emphasizing privacy and ease of use.

Top Features:

• Note-taking: Customizable templates for session documentation.
• Billing: Efficient tools for invoicing and insurance claims.
• Client management: Comprehensive client tracking and management.

Pros:

• Strong privacy features.
• Easily customizable notes.
• Convenient billing integration.

Cons:

• Limited to mental health applications.
• Can feel restrictive for larger practices.

Integrations: Compatible with major billing and insurance platforms, enhancing functionality.

Support: My Clients Plus provides customer service via phone at +1 (877) 288-5583, available Monday through Friday, 8:00 AM to 8:00 PM EST. Email support is also available at info@myclientsplus.com. 

Ratings and reviews: Users find the software intuitive, with high ratings of 4.7 on Capterra and 4.6 on G2.

Pricing:

• Basic: $29/month.
• Plus: $49/month, offering additional features.

7. Carepatron

Carepatron enhances healthcare engagement through sophisticated tools supporting collaborative workflows.

Top Features:

• Collaboration tools: Facilitates teamwork among healthcare professionals.
• Secure messaging: HIPAA-compliant messaging for patient-provider interaction.
• Task management: Simplifies following up on tasks and to-dos.

Pros:

• Strong collaboration features.
• Secure communication.
• Efficient task management.

Cons:

• May require training to maximize features.
• Integration options are more limited compared to competitors.

Integrations: Few integrations are available, focusing on core healthcare systems.

Support: Carepatron offers customer service through phone, email, and live chat support. While specific support hours are not explicitly stated, they provide 24/7 live representative assistance. 

Ratings and reviews: Users find the software intuitive, with high ratings of 4.7 on Capterra and 4.6 on G2.

Pricing:

• Professional: $49/month per user.

8. Theralytics

Theralytics is designed to support therapists and rehabilitation specialists, prioritizing simplicity and reliability.

Top Features:

• Scheduling: Efficient calendar tools for appointment management.
• Billing: Simplifies claim processing and payment tracking.
• Documentation: Easy-to-use templates for patient records.

Pros:

• User-friendly interface.
• Strong focus on therapy and rehabilitation.
• Effective billing solutions.

Cons:

• Limited scope for larger practices.
• Some users mention restricted customizability.

Integrations: Compatible with basic accounting tools to ensure smooth financial processes.

Support: Theralytics provides customer service through phone at (866) 710-3590 and email at info@theralytics.net. While specific support hours are not explicitly stated, they offer a Weekly Open Support Room every Saturday from 11:00 AM to 12:00 PM EST on Zoom.

Ratings and reviews: Users express satisfaction with Theralytics' functionality, rated at 4.6 stars on Capterra and 4.4 on G2.

Pricing: Custom pricing plans based on usage and features.

9. Healee

Healee stands out with its telehealth-oriented platform, offering flexible and secure virtual care options.

Top Features:

• Video consultations: Secure, high-quality telehealth services.
• Patient intake: Streamlines patient onboarding.
• Appointment scheduling: Integrated tools for efficient calendar management.

Pros:

• Exceptional telehealth capabilities.
• Simplified onboarding process.
• Secure communication.

Cons:

• Primarily focused on telehealth, limiting wider applicability.
• Some advanced features require additional configuration.

Integrations: Offers integrations with EMR systems and appointment scheduling platforms.

Support: Healee provides customer service via email at support@healee.com. While specific support hours are not explicitly stated, they commit to responding within one business day.

Ratings and reviews: Users value Healee's telehealth emphasis, earning a 4.7 rating on Capterra and 4.6 on G2.

Pricing:

• Standard: $39/month.
• Premium: Quote-based pricing for advanced features.

10. MediOffice

MediOffice provides an integrated practice management solution, aiming to improve healthcare efficiency.

Top Features:

• EMR management: Comprehensive patient data management.
• Clinical workflow tools: Optimizes practice operations.
• Patient engagement: Enhances interaction through various communication channels.

Pros:

• Holistic practice management.
• Optimized workflow features.
• Comprehensive communication tools.

Cons:

• Might require training for complex features.
• Limited advanced customization.

Integrations: Integrates with popular EMR and accounting software to facilitate seamless practice operations.

Support: MediOffice provides customer service through a ticketing system accessible from the MediOffice Help menu and via email at support@medioffice.co.uk, available Monday to Friday, 9:00 AM to 5:00 PM UK time. For emergencies outside these hours, an on-call support number is available at 07766 103 424.

Ratings and reviews: MediOffice is praised for its reliability, holding a Capterra rating of 4.6 and G2 of 4.5.

Pricing: Pricing tailored to firm size and specific features required.

11. My Best Practice

My Best Practice is tailored for therapy-focused environments, providing robust tools to manage daily operations.

Top Features:

• Note-taking: Supports structured and freeform documentation.
• Client management: Streamlines client data handling.
• Invoicing: Simplifies financial transactions.

Pros:

• Precisely designed for therapy settings.
• Easy note management.
• Secure client data handling.

Cons:

• Primarily suited for smaller practices.
• Some limitations in feature scalability.

Integrations: Minimal integrations, mainly focused on payment gateways and accounting software.

Support: My Best Practice offers customer service via email at support@mbpractice.com. While specific support hours are not explicitly stated, they provide assistance from initial setup and system migration to customer support throughout the year.

Ratings and reviews: Typically receives positive feedback for its efficiency, with a 4.7 rating on Capterra and 4.6 on G2.

Pricing:

• Starter Plan: $35/month.
• Professional Plan: $55/month.

12. Legwork

Legwork specializes in creating streamlined workflows and patient engagement strategies within practices.

Top Features:

• Patient communication: Tools for improved interaction and follow-up.
• Marketing automation: Enhances patient outreach.
• Appointment booking: Simplifies scheduling processes.

Pros:

• Focused on patient interaction.
• Strong marketing features.
• Efficient scheduling.

Cons:

• Limited applicability for larger practices.
• Basic batch processing functions.

Integrations: Supports integration with marketing and scheduling tools, optimizing workflow efficiency.

Support: Legwork provides customer service via phone at 877-311-4690 and email at support@legwork.com. While specific support hours are not explicitly stated, they offer assistance through their Help Center.

Ratings and reviews: Legwork garners praise for its marketing tools, receiving 4.7 stars on Capterra and 4.6 on G2.

Pricing: Custom pricing based on organization needs and tool utilization.

13. Mend

Mend provides comprehensive tools to enhance healthcare delivery with a particular emphasis on patient communication.

Top Features:

• Video conferencing: High-quality telemedicine services.
• Reminders: Automates patient notification processes.
• Patient feedback tools: Encourages continuous improvement.

Pros:

• Seamless communication features.
• Reliable telehealth integration.
• Automated reminders.

Cons:

• Integration setup can be complex.
• Requires an onboarding phase for maximal usage.

Integrations: Connects with EMR systems and scheduling applications to streamline patient care.

Support: Mend provides customer service via phone at 1-866-934-2713. While specific support hours are not explicitly stated, they offer assistance through their Contact Us page.

Ratings and reviews: Mend is hailed for its reliability and functionality, with ratings of 4.8 on Capterra and 4.7 on G2.

Pricing: Contact sales for detailed pricing based on organizational needs.

14. Pabau

Pabau offers a cloud-based CRM and practice management solution designed for medical spas and clinics.

Top Features:

• CRM tools: Enhances patient relationship management.
• Data analytics: Provides insights into practice performance.
• Marketing tools: Supports patient retention initiatives.

Pros:

• Comprehensive CRM capabilities.
• Helpful data analytic features.
• Effective marketing tools.

Cons:

• Limited customization for certain features.
• Some users find navigation complex.

Integrations: Integrates with various healthcare and finance systems, allowing for comprehensive data management.

Support: Pabau provides customer service through various channels, including support tickets, video call support, and assisted chat. Their support is available 21 hours per day, ensuring assistance across multiple time zones. Specific support hours are not explicitly stated. 

Ratings and reviews: Known for its CRM strength, Pabau holds strong ratings of 4.6 on Capterra and 4.5 on G2.

Pricing: Pricing details are available upon request, tailored to specific requirements.

15. BestoSys

BestoSys is a versatile platform providing tools for comprehensive practice management across diverse medical fields.

Top Features:

• Appointment scheduling: Efficient tools for managing patient flow.
• Billing and invoicing: Streamlines financial transactions.
• Inventory management: Tracks and manages medical supplies.

Pros:

• Broad feature set.
• Strong billing system.
• Effective inventory control.

Cons:

• Some features require additional configuration.
• Mostly suitable for small to medium practices.

Integrations: Supports integration with billing and EMR systems for enhanced practice management.

Support: BestoSys provides customer service via phone at +91-97673 77819 and email at support@bestosys.com. While specific support hours are not explicitly stated, they emphasize accessibility, stating that users should be able to access their practice data anytime, anywhere, whether during working hours or after, on weekly offs or holidays.

Ratings and reviews: BestoSys is especially valued for its comprehensive features and ease of use, with ratings of 4.7 on Capterra and 4.6 on G2.

Pricing: Flexible pricing options tailored to specific business needs. Contact sales for detailed plans.

What features to look for when researching the top patient portal vendors?

When evaluating patient portal vendors, it’s essential to consider features that enhance usability, security, and integration with existing healthcare systems.

1. User-friendly interface

A patient portal should be intuitive and easy to navigate.

Look for vendors that prioritize user experience to ensure patients, regardless of their technical skills, can access and utilize the portal effectively.

2. Security and compliance

Ensure the software complies with regulations such as HIPAA for securing patient data.

Robust encryption and authentication features are crucial for maintaining privacy and trust.

3. Integration capabilities

The ability to seamlessly integrate with existing healthcare systems, like electronic health records (EHR), is essential.

This facilitates smooth data flow and helps healthcare providers maintain comprehensive patient information.

4. Communication tools

Consider portals that offer secure messaging between patients and providers.

This functionality supports timely communication, increasing patient engagement and satisfaction.

5. Appointment scheduling

Look for features that allow patients to manage appointments online.

This convenience can improve patient adherence to scheduled visits and reduce administrative burdens on healthcare staff.

6. Patient education resources

Portals that include educational content can empower patients with knowledge about their health conditions and treatments.

This resource helps improve health literacy and patient engagement.

7. Billing and payment options

A comprehensive portal should offer billing management and payment processing.

Patients appreciate the convenience of managing bills online.

8. Customization options

Vendors that offer customizable features can better meet the specific needs of a healthcare provider.

Tailoring the portal ensures it aligns with a practice's workflow and patient demographics.

9. Mobile accessibility

With the increasing use of smartphones, mobile-friendly patient portals are essential.

They provide flexibility and improve access to healthcare services for patients on the go.

“Discover how seamless integrations can enhance patient interactions and streamline workflows by exploring Keragon’s integrations.”

Which of the patient portal software companies is right for your practice?

Selecting the right patient portal software for a practice depends on various factors including functionality, ease of integration, and specific needs of healthcare providers.

EHR YOUR WAY is a notable choice for those in behavioral health and addiction treatment. Its customizable features make it versatile, allowing practices to tailor their systems effectively.

In the modern healthcare landscape, a seamless integration with existing systems is crucial.

Practices should seek software that offers robust features without disrupting current workflows.

Pricing is another essential consideration.

Practices must assess software costs alongside features to ensure alignment with budget constraints.

When evaluating options, it’s beneficial to look at reviews and comparisons from credible sources.

They provide insights into deployment strategies and unique benefits each system offers.

Optimizing Patient Portals with Custom Software

When evaluating patient portal solutions, it's also crucial to consider healthcare software development as a key factor in customization, integration, and long-term scalability.

A well-developed software solution ensures seamless interoperability, robust security, and an enhanced user experience for both patients and healthcare providers.

Companies like Enterprise64 specialize in developing tailored healthcare software solutions that help medical practices optimize efficiency and enhance patient engagement.

Final thoughts on the best patient portal software solutions

Patient portal software solutions are essential tools for improving patient engagement, streamlining healthcare processes, and enhancing communication between patients and providers. 

The best solutions offer features like secure messaging, appointment scheduling, access to medical records, and billing transparency, all while ensuring compliance with HIPAA and other regulations. 

Key players in the industry provide user-friendly interfaces, integration with electronic health records (EHR), and customizable options to meet the needs of various healthcare practices. 

Ultimately, the most important consideration when choosing a patient portal is its ability to improve patient outcomes and satisfaction while optimizing the efficiency of healthcare delivery.

“Get started with Keragon’s automation platform to enhance efficiency and improve patient experiences by signing up for free today.”

FAQ

Who are the top patient portal vendors in 2025?

The top patient portal vendors offer advanced solutions that improve patient engagement, streamline communication, and enhance data security. Leading patient portal software companies focus on features like secure messaging, online scheduling, and integration with electronic health records (EHRs). 

When choosing a vendor, healthcare providers should consider ease of use, security compliance, and interoperability with existing healthcare systems.

What features should the best patient portals include?

The best patient portals provide secure access to medical records, enable direct communication with healthcare providers, and support online appointment scheduling. 

Additionally, patient portal software vendors develop solutions that offer mobile accessibility, prescription refill requests, and billing management. These features ensure that patients can actively participate in their healthcare while reducing administrative burdens for providers.

How do patient portal systems improve healthcare efficiency?

Patient portal systems enhance healthcare efficiency by automating administrative tasks, reducing paperwork, and improving patient-provider communication. Leading patient portal vendors create user-friendly platforms that integrate seamlessly with existing healthcare technologies. 

These solutions help healthcare organizations optimize workflow, increase patient satisfaction, and maintain compliance with industry regulations.